Description

3,3,3-Trifluoropropanal is a versatile fluorinated aldehyde building block essential for advanced organic synthesis. Its unique trifluoromethyl group imparts significant lipophilicity and metabolic stability to target molecules, making it a critical intermediate for high-value applications. This compound is primarily sought after by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty materials sectors.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated active pharmaceutical ingredients (APIs) and drug candidates, leveraging the "fluorine effect" to enhance bioavailability and binding affinity.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and insecticides where the trifluoromethyl group improves pesticidal activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving dielectric anisotropy and thermal stability.
• Polymer & Resin Modifier: Incorporated to create specialty fluoropolymers with enhanced chemical resistance, low surface energy, and improved weatherability.
• Organic Synthesis Reagent: A valuable electrophile in nucleophilic addition reactions, Grignard reactions, and reductive amination for introducing the CF3-CH2- moiety.
• Fluorinated Surfactant Precursor: Used to synthesize surfactants and surface treatment agents with superior spreading and leveling properties.

Basic Information

Product Name	3,3,3-Trifluoropropanal
CAS No.	460-40-2
Molecular Formula	C3H3F3O
Molecular Weight	112.05 g/mol
Synonyms	3,3,3-Trifluoropropionaldehyde; 3,3,3-Trifluoropropanaldehyde; Trifluoropropanal; 3,3,3-Trifluoropropane-1-al; Perfluoropropanal; 1,1,1-Trifluoropropanal; 2,2,2-Trifluoroethanecarboxaldehyde; TFPAL
EINECS	207-311-9

Quality Control

Our 3,3,3-Trifluoropropanal is manufactured under strict quality management systems. Each batch is analyzed to ensure it meets stringent purity and consistency standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically ≥97% by GC), and impurity profiles is provided with every shipment to guarantee reliable performance in your processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, well-ventilated place. Recommended storage temperature is 2-8°C to minimize volatility and oxidation. Keep away from strong bases, reducing agents, and oxidizers.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.