Description

4'-Fluoropropiophenone is a high-purity fluorinated aromatic ketone, a key building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules, particularly in the pharmaceutical sector. This compound is essential for researchers and manufacturers in pharmaceutical R&D, agrochemical production, and material science who require reliable, high-quality synthetic precursors.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various active pharmaceutical ingredients (APIs), including potential central nervous system (CNS) agents and other fluorinated drug candidates.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, where the fluorine atom can enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Material Research: Serves as a starting material for synthesizing fluorinated organic compounds used in electronic displays and optoelectronic devices.
• Organic Synthesis Building Block: Employed in Friedel-Crafts acylation, Grignard reactions, and reduction processes to introduce the propiophenone moiety into more complex structures.
• Chemical Research & Development: Utilized in academic and industrial labs for method development and exploring new fluorination chemistry and reaction pathways.

Basic Information

Product Name	4'-Fluoropropiophenone
CAS No.	456-03-1
Molecular Formula	C9H9FO
Molecular Weight	152.17 g/mol
Synonyms	1-(4-Fluorophenyl)propan-1-one; p-Fluoropropiophenone; 4-Fluoropropiophenone; Propiophenone, 4'-fluoro-; USFDA 456-03-1; 4-Fluorophenyl ethyl ketone; 4'-Fluoropropiophenon; 1-Propanone, 1-(4-fluorophenyl)-
EINECS	Contact for details

Quality Control

Our 4'-Fluoropropiophenone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	34°C - 38°C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.