Description

3-Fluoro-4-Methoxyacetophenone is a versatile fluorinated aromatic ketone building block of significant importance in advanced organic synthesis. Its unique structure, featuring both electron-donating (methoxy) and electron-withdrawing (fluoro, carbonyl) groups, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a fluorinated aromatic scaffold for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atom can improve biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal compounds used in display technologies.
• Organic Electronic Materials: Employed in the development of organic semiconductors and charge-transport materials for OLEDs and photovoltaic cells.
• Chemical Research & Development: A valuable reagent for method development, catalysis studies, and exploring new reaction pathways in academic and industrial labs.
• Fine Chemical Production: Used in the custom synthesis of specialty chemicals, flavors, and fragrances.

Basic Information

Product Name	3-Fluoro-4-Methoxyacetophenone
CAS No.	455-91-4
Molecular Formula	C9H9FO2
Molecular Weight	168.16 g/mol
Synonyms	1-(3-Fluoro-4-methoxyphenyl)ethanone; 3'-Fluoro-4'-methoxyacetophenone; 4'-Methoxy-3'-fluoroacetophenone; 3-Fluoro-4-methoxyacetophenone; 3-Fluoro-p-anisyl methyl ketone; 3-Fluoro-4-methoxyphenyl methyl ketone; 1-Acetyl-3-fluoro-4-methoxybenzene
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-Methoxyacetophenone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support custom synthesis and can tailor purity grades, including research and GMP grades, to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.