Description

3-Fluoropropiophenone is a versatile fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its value lies in the strategic introduction of a fluorine atom and a reactive carbonyl group, enabling precise molecular modifications. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, including potential CNS-active compounds and enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where fluorine incorporation enhances biological activity and stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic semiconductors and liquid crystal molecules in display technologies.
• Organic Synthesis Building Block: Employed in Friedel-Crafts acylation, Grignard reactions, and reductive amination to create complex fluorinated structures.
• Chemical Research & Development: A valuable reagent for exploring new fluorination methodologies and structure-activity relationships (SAR) in medicinal chemistry.

Basic Information

Product Name	3-Fluoropropiophenone
CAS No.	455-67-4
Molecular Formula	C9H9FO
Molecular Weight	152.17 g/mol
Synonyms	1-(3-Fluorophenyl)propan-1-one; 3-Fluoropropiophenone; m-Fluoropropiophenone; 3'-Fluoropropiophenone; Propiophenone, 3'-fluoro-; 3-Fluorophenyl ethyl ketone; 3-Fluoro-1-phenyl-1-propanone; 455-67-4
EINECS	Contact for details

Quality Control

Our 3-Fluoropropiophenone is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, keep the container tightly sealed to minimize exposure to atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.