Description

4-Fluorophenyl Methyl Sulfone is a versatile organosulfur compound featuring a sulfone functional group attached to a fluorinated aromatic ring. This structural motif makes it a valuable building block and intermediate in advanced organic synthesis, particularly for the development of pharmaceuticals and agrochemicals. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), especially those containing sulfone or fluorophenyl moieties for therapeutic applications.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and stability.
• Material Science Research: Serves as a monomer or precursor for developing novel polymers, liquid crystals, or advanced materials with specific electronic or thermal properties.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Organic Synthesis Building Block: Utilized in nucleophilic aromatic substitution and as a directing group in metalation reactions for regioselective functionalization.
• Chemical Research & Development: Employed in academic and industrial labs for method development and exploring new reaction pathways in synthetic chemistry.

Basic Information

Product Name	4-Fluorophenyl Methyl Sulfone
CAS No.	455-15-2
Molecular Formula	C7H7FO2S
Molecular Weight	174.19 g/mol
Synonyms	1-Fluoro-4-(methylsulfonyl)benzene; p-Fluorophenyl Methyl Sulfone; (4-Fluorophenyl)(methyl)sulfone; Methyl 4-fluorophenyl sulfone; 4-Fluoro-1-(methylsulfonyl)benzene; 4-Fluorobenzyl Methyl Sulfone (common misnomer); 4-Fluorophenylmethanesulfone
EINECS	Contact for details

Quality Control

Our 4-Fluorophenyl Methyl Sulfone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed specifications for traceability and quality assurance. Our standard grade meets the rigorous demands of industrial synthesis, and we can support development with custom purity grades upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.