Description

3-Fluoro-1,2-Propanediol is a versatile fluorinated diol building block, offering unique reactivity and polarity for advanced chemical synthesis. Its bifunctional nature, featuring both hydroxyl groups and a fluorine atom, makes it a valuable intermediate for introducing fluorinated segments into target molecules. This compound is particularly relevant for researchers and manufacturers in the pharmaceutical and agrochemical sectors seeking to modify the physicochemical properties of their products.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel fluorinated active pharmaceutical ingredients (APIs) and prodrugs, potentially enhancing metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in creating advanced fluorinated pesticides, herbicides, and fungicides, where the fluorine atom can improve efficacy and environmental profile.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for producing specialty fluorinated polymers, coatings, and resins with tailored surface properties.
• Liquid Crystal & Electronic Chemicals: A precursor in the manufacture of fluorinated liquid crystals and dielectric fluids for display and electronic applications.
• Organic Synthesis & Catalysis: A versatile reagent for constructing complex fluorinated organic molecules and as a ligand or modifier in catalytic systems.
• Bioconjugation & Probe Development: Useful for synthesizing fluorinated linkers and probes used in biochemical research and diagnostic assays.

Basic Information

Product Name	3-Fluoro-1,2-Propanediol
CAS No.	453-16-7
Molecular Formula	C3H7FO2
Molecular Weight	94.08 g/mol
Synonyms	3-Fluoro-1,2-dihydroxypropane; 1,2-Propanediol, 3-fluoro-; 3-Fluoropropane-1,2-diol; 3-Fluoropropylene glycol; (±)-3-Fluoro-1,2-propanediol; 3-Fluoro-propane-1,2-diol; 3-Fluoropropanediol; NSC 37744
EINECS	Contact for details

Quality Control

We supply 3-Fluoro-1,2-Propanediol in various purity grades to meet diverse application needs, from research to commercial scale. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. For specific regulatory requirements such as GMP, ICH guidelines, or custom specifications, please contact our technical team.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent absorption of atmospheric moisture, which can affect product quality and stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC/HPLC)	≥95.0% (Standard Grade)
Water Content (KF)	≤1.0%
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.