Description

3-Fluoro-1-(4-Hydroxyphenyl)Propan-1-One is a versatile fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a phenolic hydroxyl group and a fluorinated alkyl ketone moiety, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal compounds used in display technologies.
• Polymer Modification: Employed to introduce fluorine and phenolic functionalities into polymer chains, altering thermal and chemical resistance properties.
• Organic Electronics: Acts as a precursor for materials used in organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Research & Development: A valuable reagent for exploring new fluorination reactions and creating specialized chemical libraries for screening.

Basic Information

Product Name	3-Fluoro-1-(4-Hydroxyphenyl)Propan-1-One
CAS No.	451-44-5
Molecular Formula	C9H9FO2
Molecular Weight	168.16 g/mol
Synonyms	3'-Fluoropropiophenone-4'-ol; 1-(4-Hydroxyphenyl)-3-fluoropropan-1-one; 4'-Hydroxy-3'-fluoropropiophenone; 3-Fluoro-1-(4-hydroxyphenyl)-1-propanone; 3-Fluoro-4'-hydroxypropiophenone; 4-Hydroxy-3-fluoropropiophenone; p-Hydroxy-3-fluoropropiophenone; 451-44-5
EINECS	Contact for details

Quality Control

Our production of 3-Fluoro-1-(4-Hydroxyphenyl)Propan-1-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing parameters such as assay, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.