Description

Phenylmandelic Acid CAS NO 450-52-2 is an important chiral aromatic α-hydroxy acid, serving as a key intermediate in organic synthesis. Its primary value lies in its utility as a versatile building block for pharmaceuticals and fine chemicals, particularly in the synthesis of chiral drugs and active pharmaceutical ingredients (APIs). This compound is essential for research laboratories, pharmaceutical manufacturers, and fine chemical producers engaged in asymmetric synthesis and the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial chiral precursor in the synthesis of various active pharmaceutical ingredients (APIs), especially those requiring specific stereochemistry.
• Asymmetric Synthesis: Used as a starting material or resolving agent in the production of enantiomerically pure compounds for drug development.
• Fine Chemical Production: Serves as a building block for complex organic molecules used in agrochemicals, dyes, and specialty materials.
• Biochemical Research: Employed in enzymatic studies and as a standard in analytical method development for chiral separation techniques like HPLC.
• Chemical Reference Standard: Utilized as a high-purity standard for quality control and calibration in analytical laboratories.

Basic Information

Product Name	Phenylmandelic Acid
CAS No.	450-52-2
Molecular Formula	C14H12O3
Molecular Weight	228.24 g/mol
Synonyms	α-Hydroxy-α-phenylbenzeneacetic Acid; (±)-Mandelic Acid Phenyl Ester; DL-Phenylmandelic Acid; 2-Hydroxy-2,2-diphenylacetic Acid; Benzilic Acid, α-Hydroxy-; Diphenylglycolic Acid; Phenylbenzilic Acid; 2,2-Diphenyl-2-hydroxyacetic Acid
EINECS	207-178-5

Quality Control

Our Phenylmandelic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure it meets the high standards required for pharmaceutical and research applications. We provide detailed Certificates of Analysis (COA) with key parameters including assay, chiral purity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring reliable and consistent material for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	148°C - 152°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.