Description

5'-Fluoro-2'-Hydroxypropiophenone is a versatile fluorinated aromatic ketone intermediate of significant importance in advanced organic synthesis. Its core value lies in the strategic placement of fluorine and hydroxyl groups, which allows for precise structural modifications in target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity and stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for the synthesis of fluorinated organic molecules used in electronic displays and optoelectronic devices.
• Advanced Organic Synthesis: Employed in cross-coupling reactions, carbonyl chemistry, and as a precursor for heterocyclic compounds in academic and industrial research.
• Chemical Research & Development: A valuable reagent for exploring new synthetic methodologies and creating compound libraries for high-throughput screening.

Basic Information

Product Name	5'-Fluoro-2'-Hydroxypropiophenone
CAS No.	443-09-4
Molecular Formula	C9H9FO2
Molecular Weight	168.16 g/mol
Synonyms	1-(5-Fluoro-2-hydroxyphenyl)propan-1-one; 2-Hydroxy-5-fluoropropiophenone; 5-Fluoro-2-hydroxypropiophenone; 5-Fluoro-2'-hydroxypropiophenone; 2'-Hydroxy-5'-fluoropropiophenone; 1-Propanone, 1-(5-fluoro-2-hydroxyphenyl)-; 5-Fluoro-2-hydroxy-1-phenylpropan-1-one
EINECS	207-138-5

Quality Control

Our 5'-Fluoro-2'-Hydroxypropiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.