Description

3-Chloro-2,2,3-Trifluoropropionic Acid is a specialized fluorinated carboxylic acid building block, offering a unique combination of reactivity and fluorine-derived properties. This compound is critical for introducing the trifluoromethyl moiety and chlorine functionality into target molecules, enabling the synthesis of advanced materials and active ingredients. It is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring precise molecular tuning.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the fluorine atoms contribute to improved efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, contributing to desired dielectric and optical properties.
• Polymer Modification: Employed to introduce fluorinated side chains into polymers, enhancing chemical resistance, surface properties, and thermal stability.
• Organic Synthesis Reagent: Acts as a versatile reagent for introducing the -CF2COOH group or for further derivatization via its acid chloride.
• Fluorinated Surfactant Precursor: Used in the manufacture of high-performance surfactants and surface treatment agents for demanding industrial applications.

Basic Information

Item	Details
Product Name	3-Chloro-2,2,3-Trifluoropropionic Acid
CAS No.	425-97-8
Molecular Formula	C3H2ClF3O2
Molecular Weight	162.49 g/mol
Synonyms	3-Chloro-2,2,3-trifluoropropanoic Acid; 2,2,3-Trifluoro-3-chloropropionic Acid; α,α,β-Trifluoro-β-chloropropionic Acid; 3-Chlorotrifluoropropionic Acid; CF3CClFCOOH; 425-97-8; 3-Chloro-2,2,3-trifluoropropionate
EINECS	Contact for details

Quality Control

Our 3-Chloro-2,2,3-Trifluoropropionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is sensitive to strong bases and fluorides; keep away from incompatible substances. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.