Description

2,2,3,3-Tetrafluoro-1,4-Butanediol is a high-value fluorinated diol building block, distinguished by its unique perfluorinated carbon chain. This structure is critical for introducing fluorine's beneficial properties—such as enhanced chemical stability, hydrophobicity, and thermal resistance—into advanced polymers and materials. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and specialty polymer industries for synthesizing novel fluorinated compounds and high-performance materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon for introducing fluorine atoms into active pharmaceutical ingredients (APIs) to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the development of novel fluorinated pesticides and herbicides, where fluorine enhances activity and environmental persistence.
• Fluoropolymer Modification: Acts as a monomer or chain extender to create specialty polyurethanes, polyesters, and epoxy resins with improved solvent resistance and low surface energy.
• Surface Active Agents: Employed in the synthesis of fluorinated surfactants and coatings for exceptional oil- and water-repellency.
• Electrolyte Additive: Investigated for use in lithium-ion battery electrolytes to improve high-voltage stability and safety.
• Cross-linking Agent: Utilized in the formulation of high-performance adhesives and sealants requiring chemical inertness.

Basic Information

Product Name	2,2,3,3-Tetrafluoro-1,4-Butanediol
CAS No.	425-61-6
Molecular Formula	C4H4F4O2
Molecular Weight	160.07 g/mol
Synonyms	1,4-Butanediol, 2,2,3,3-tetrafluoro-; 2,2,3,3-Tetrafluorobutane-1,4-diol; Tetrafluorobutanediol; Perfluorobutanediol; 1,1,2,2-Tetrafluoro-1,4-butanediol; HOCH2CF2CF2CH2OH; 2,2,3,3-Tetrafluoro-1,4-dihydroxybutane
EINECS	207-049-3

Quality Control

Our 2,2,3,3-Tetrafluoro-1,4-Butanediol is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from strong alkalis and fluorides.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.