Description

2-Bromo-1,1,1-Trifluoroethane is a halogenated alkane derivative that serves as a versatile building block in advanced chemical synthesis. Its unique combination of bromine and fluorine atoms makes it a valuable reagent for introducing trifluoroethyl groups and for use as a solvent or intermediate in demanding applications. This compound is primarily sought by R&D laboratories and industrial manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors for developing novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring the incorporation of a trifluoroethyl moiety to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Serves as a key precursor in the production of advanced herbicides, pesticides, and fungicides, where the fluorine content can enhance activity and environmental persistence.
• Fluorinated Polymer & Material Science: Acts as a monomer or modifying agent in the creation of specialty polymers, coatings, and materials with improved chemical resistance, thermal stability, and low surface energy.
• Organic Synthesis Reagent: Employed as an alkylating agent or as a source of the -CF3 group in nucleophilic substitution and other coupling reactions within research and process chemistry.
• Refrigerant & Fire Suppressant Formulation: Utilized in the development of next-generation, environmentally regulated fluorocarbon blends for specialized cooling and fire extinguishing systems.
• Analytical Chemistry & Spectroscopy: May be used as a standard or reference compound in gas chromatography (GC) and mass spectrometry (MS) analyses.

Basic Information

Product Name	2-Bromo-1,1,1-Trifluoroethane
CAS No.	421-06-7
Molecular Formula	C2H2BrF3
Molecular Weight	162.94 g/mol
Synonyms	1,1,1-Trifluoro-2-bromoethane; Bromotrifluoroethane; Halothane Impurity B; Freon 123B1; FC-123B1; R-123B1; Trifluoroethyl bromide; 2-Bromotrifluoroethane
EINECS	207-000-8

Quality Control

Every batch of 2-Bromo-1,1,1-Trifluoroethane is produced and tested under a stringent quality management system. We provide comprehensive analytical data to ensure the product meets the precise requirements of your application, whether for research or scaled manufacturing. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. Our quality commitment supports compliance with cGMP, ISO, and other relevant regulatory frameworks for industrial and laboratory use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept upright and sealed when not in use. Recommended storage temperature is 2-25°C. Keep away from strong bases and reactive metals.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Density (at 20°C)	1.80 - 1.82 g/mL
Boiling Point	~ 46-48°C
Related Substances (GC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.