Description

2-Chloro-2-Fluoropropane is a versatile halogenated hydrocarbon building block of significant interest in advanced chemical synthesis. Its value lies in its unique molecular structure, which combines chlorine and fluorine atoms on the same carbon, making it a valuable intermediate for introducing fluorinated moieties. This compound is primarily needed by research and development laboratories, agrochemical manufacturers, and pharmaceutical companies engaged in the development of novel active ingredients and specialty materials. Its high volatility also makes it a candidate for specialized applications in electronics and refrigerant formulation.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of fluorinated active pharmaceutical ingredients (APIs) and novel drug candidates.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the fluorine atom enhances biological activity and stability.
• Organic Synthesis Reagent: Serves as a versatile reagent for introducing the -CFCl- group in complex molecule construction for fine chemicals.
• Refrigerant & Propellant Research: Investigated as a potential component or intermediate in next-generation, low-global-warming-potential (GWP) fluorocarbon blends.
• Electronics Industry: May be used in plasma etching or as a precursor in the chemical vapor deposition (CVD) of fluorinated thin films.
• Polymer Modification: Acts as a monomer or modifier in the synthesis of specialty fluoropolymers with unique surface properties.

Basic Information

Product Name	2-Chloro-2-Fluoropropane
CAS No.	420-44-0
Molecular Formula	C₃H₆ClF
Molecular Weight	96.53 g/mol
Synonyms	Propane, 2-chloro-2-fluoro-; 2-Fluoro-2-chloropropane; Freon 251cb; HCFC-251cb; 1,1-Dimethyl-1-fluoro-1-chloroethane; α-Fluoro-α-chloropropane; 2-Chloro-2-fluoropropane; 2-Fluoroisopropyl chloride
EINECS	206-997-1

Quality Control

Our 2-Chloro-2-Fluoropropane is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analysis using GC, GC-MS, and NMR to verify identity and quantify impurities. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, water content, and specific impurity profiles. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong bases and reactive metals. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration of vapors. Recommended storage temperature is 2-8°C for long-term stability, though short-term storage at controlled room temperature (15-25°C) is acceptable.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Density at 20°C	1.05 - 1.10 g/mL
Boiling Point	Approx. 45-50°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.