Description

4,4′-Difluorodiphenyl Sulfide is a high-purity organic sulfur compound featuring a central sulfide bridge flanked by fluorinated aromatic rings. This specific molecular architecture makes it a valuable building block (synthon) and key intermediate in advanced chemical synthesis. It is primarily sought after by R&D laboratories and industrial manufacturers in the pharmaceutical and agrochemical sectors, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging the fluorine atoms for enhanced bioactivity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a core structure in the production of specialty chemicals for electronic displays and organic light-emitting diodes due to its rigid, fluorinated biphenyl system.
• Polymer & Resin Modifier: Incorporated into high-performance polymers to impart specific properties like thermal stability, chemical resistance, or altered dielectric characteristics.
• Ligand & Catalyst Precursor: Utilized in organometallic chemistry and catalysis research to create novel ligands for transition metal complexes.
• Organic Synthesis Reagent: Acts as a versatile reagent in cross-coupling reactions and other organic transformations to construct complex molecular architectures.

Basic Information

Product Name	4,4′-Difluorodiphenyl Sulfide
CAS No.	404-38-6
Molecular Formula	C12H8F2S
Molecular Weight	222.25 g/mol
Synonyms	Bis(4-fluorophenyl) sulfide; 4,4'-Difluorodiphenyl sulfide; 1-Fluoro-4-[(4-fluorophenyl)sulfanyl]benzene; p,p'-Difluorodiphenyl sulfide; 4-Fluorophenyl 4-fluorophenyl sulfide; (4-Fluorophenyl)(4-fluorophenyl) sulfide; NSC 404124
EINECS	206-966-3

Quality Control

Our 4,4′-Difluorodiphenyl Sulfide is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC and GC analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.