Description

4'-Fluoro-2-Hydroxyacetophenone is a versatile fluorinated aromatic ketone and a key organic synthetic intermediate. This compound is valued for its unique molecular structure, which combines a reactive acetyl group with a phenolic hydroxyl and a fluorine substituent, enabling precise chemical modifications. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of advanced active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for high-performance displays.
• Organic Light-Emitting Diodes (OLEDs): Acts as a key intermediate for electron-transport or host materials in OLED device fabrication.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new fluorination reactions and creating complex molecular architectures.
• Fine Chemical Production: Utilized in the custom synthesis of specialty chemicals, dyes, and functional materials.

Basic Information

Product Name	4'-Fluoro-2-Hydroxyacetophenone
CAS No.	403-31-6
Molecular Formula	C8H7FO2
Molecular Weight	154.14 g/mol
Synonyms	1-(4-Fluoro-2-hydroxyphenyl)ethanone; 2'-Hydroxy-4'-fluoroacetophenone; 4-Fluoro-2-hydroxyacetophenone; 2-Acetyl-5-fluorophenol; 5-Fluoro-2-hydroxyacetophenone; 4'-Fluoro-2'-hydroxyacetophenone; 1-(2-Hydroxy-4-fluorophenyl)ethan-1-one
EINECS	Contact for details

Quality Control

Our 4'-Fluoro-2-Hydroxyacetophenone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates, including cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and incompatible materials. The container should be kept tightly sealed to minimize moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.