Description

2-Bromo-4'-Fluoroacetophenone is a versatile and high-purity organic building block, specifically a halogenated acetophenone derivative. Its molecular structure makes it a critical intermediate for synthesizing more complex molecules in advanced research and industrial applications. This compound is essential for pharmaceutical chemists, agrochemical researchers, and material scientists engaged in the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing fluorinated and brominated aromatic systems.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and pesticides, leveraging the bioactivity of the fluoro and bromo substituents.
• Material Science Research: Serves as a building block for creating specialized polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: Employed in organic synthesis as a starting material for cross-coupling reactions, nucleophilic substitutions, and the preparation of heterocyclic compounds.
• Fine Chemical Production: Utilized in the custom synthesis of complex, high-value specialty chemicals for various industrial sectors.

Basic Information

Product Name	2-Bromo-4'-Fluoroacetophenone
CAS No.	403-29-2
Molecular Formula	C8H6BrFO
Molecular Weight	217.04 g/mol
Synonyms	1-(4-Fluorophenyl)-2-bromoethanone; 2-Bromo-1-(4-fluorophenyl)ethanone; p-Fluoro-α-bromoacetophenone; 4'-Fluoro-2-bromoacetophenone; α-Bromo-4'-fluoroacetophenone; 2-Bromo-4-fluoroacetophenone; 1-(4-Fluorophenyl)-2-bromo-1-ethanone; 4-Fluorophenacyl bromide
EINECS	Contact for details

Quality Control

Our 2-Bromo-4'-Fluoroacetophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤0.5%
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.