Description

3'-Bromo-5'-Fluoro-4'-Hydroxyacetophenone is a high-purity, multi-functional halogenated aromatic ketone building block essential for advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for constructing complex molecules with tailored biological and physical properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging its halogenated structure for enhanced bioactivity.
• Liquid Crystal & OLED Material Research: Serves as a building block for creating advanced organic electronic materials due to its planar, substituted aromatic core.
• Chemical Biology & Proteomics: Employed in the design of activity-based probes (ABPs) and molecular tags for studying enzyme function.
• Advanced Polymer Chemistry: Acts as a monomer or cross-linking agent for synthesizing specialty polymers with specific thermal or optical properties.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses serving the fine chemical and life science industries.

Basic Information

Product Name	3'-Bromo-5'-Fluoro-4'-Hydroxyacetophenone
CAS No.	402-84-6
Molecular Formula	C8H6BrFO2
Molecular Weight	233.04 g/mol
Synonyms	1-(3-Bromo-5-fluoro-4-hydroxyphenyl)ethanone; 1-(3-Bromo-5-fluoro-4-hydroxyphenyl)ethan-1-one; 3-Bromo-5-fluoro-4-hydroxyacetophenone; 4'-Hydroxy-3'-bromo-5'-fluoroacetophenone; 4-Acetyl-2-bromo-6-fluorophenol; 2-Bromo-6-fluoro-4-acetylphenol; 402-84-6; NSC 403079
EINECS	Contact for details

Quality Control

Our 3'-Bromo-5'-Fluoro-4'-Hydroxyacetophenone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage or when opening a new container to maintain purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.