Description

4-Fluorobenzotrichloride is a key fluorinated aromatic intermediate of significant importance in advanced organic synthesis. Its value lies in the reactivity of the trichloromethyl group, which can be selectively transformed into various functional moieties, enabling the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and performance materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs), including potential candidates for central nervous system (CNS) drugs and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity, metabolic stability, and selectivity.
• Liquid Crystal & OLED Material Precursor: Acts as a starting material for synthesizing fluorinated aromatic cores used in liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs) to improve performance and stability.
• Polymer & Resin Modifier: Employed to introduce fluorine-containing side chains into polymers, imparting valuable properties such as chemical resistance, low surface energy, and enhanced thermal stability.
• Dye & Pigment Intermediate: Facilitates the creation of novel fluorinated dyes and pigments with improved color fastness, solubility, and application performance.
• Cross-Coupling Reactions: Functions as a substrate in various metal-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to create complex biaryl structures common in many advanced materials.

Basic Information

Product Name	4-Fluorobenzotrichloride
CAS No.	402-42-6
Molecular Formula	C7H4Cl3F
Molecular Weight	213.46 g/mol
Synonyms	p-Fluorobenzotrichloride; α,α,α-Trichloro-4-fluorotoluene; 4-Fluoro-α,α,α-trichlorotoluene; (Trichloromethyl)-4-fluorobenzene; 1-(Trichloromethyl)-4-fluorobenzene; Benzene, 1-(trichloromethyl)-4-fluoro-; 4-Fluorophenyltrichloromethane
EINECS	206-941-9

Quality Control

Our 4-Fluorobenzotrichloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (IR, NMR), to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing assay, impurity profile, and physical characteristics is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.