Description

1,3-Bis(Trifluoromethyl)-Benzene is a versatile fluorinated aromatic compound characterized by its two trifluoromethyl groups in the meta position. This structure imparts unique properties, including high volatility and excellent chemical stability, making it a valuable intermediate in advanced chemical synthesis. It is primarily sought after by manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring precise fluorination and robust molecular frameworks.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring trifluoromethylated aromatic cores for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the trifluoromethyl group improves efficacy and environmental profile.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands and organometallic catalysts used in cross-coupling and other fine chemical reactions.
• Electronic Chemicals: Employed in the development of materials for the electronics industry, including precursors for dielectric fluids and specialty solvents.
• Organic Synthesis Building Block: Utilized in research and development for introducing the trifluoromethyl group into complex organic molecules, facilitating the exploration of new chemical spaces.
• Fluorinated Polymer Modifier: Acts as a monomer or modifier in the synthesis of high-performance polymers with enhanced thermal and chemical resistance.

Basic Information

Product Name	1,3-Bis(Trifluoromethyl)-Benzene
CAS No.	402-31-3
Molecular Formula	C8H4F6
Molecular Weight	214.11 g/mol
Synonyms	m-Bis(trifluoromethyl)benzene; 1,3-Di(trifluoromethyl)benzene; m-Xylene, α,α,α,α',α',α'-hexafluoro-; Benzene, 1,3-bis(trifluoromethyl)-; α,α,α,α',α',α'-Hexafluoro-m-xylene; Hexafluoro-m-xylene; m-(Trifluoromethyl)benzotrifluoride; 402-31-3
EINECS	206-936-4

Quality Control

Our 1,3-Bis(Trifluoromethyl)-Benzene is produced under a stringent quality management system. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports your need for reliable and traceable raw materials in cGMP and ISO environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and maintain purity. Recommended storage temperature is 2-25°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	≤ 2.0% total
Density (20°C)	~1.42 g/mL
Refractive Index (n20D)	~1.38

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.