Description

2,2'-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)biphenyl is a high-purity, bifunctional boronic ester derivative that serves as a critical building block in advanced organic synthesis. Its value lies in providing a stable, protected boronic acid equivalent, enabling efficient and selective cross-coupling reactions under demanding conditions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-quality intermediates for constructing complex biphenyl-based molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biphenyl or extended aromatic systems.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the biphenyl moiety is a core structural component.
• Organic Light-Emitting Diodes (OLEDs): Acts as a building block for electron-transport materials and host materials in the production of advanced OLED displays and lighting.
• Ligand Synthesis for Catalysis: Employed in the preparation of sophisticated bidentate or polydentate ligands used in homogeneous catalysis.
• Polymer & Material Science: Serves as a monomer or cross-linking agent in the synthesis of conjugated polymers, porous organic frameworks, and other functional materials.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D focused on C-C bond formation and the exploration of new synthetic methodologies.

Basic Information

Product Name	2,2'-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)biphenyl
CAS No.	398128-09-1
Molecular Formula	C28H40B2O4
Molecular Weight	462.24 g/mol
Synonyms	2,2'-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,1'-biphenyl; [1,1'-Biphenyl]-2,2'-diylbis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane); 2,2'-Bis(pinacolboranyl)biphenyl; 2,2'-Biphenyldiboronic Acid Bis(pinacol) Ester; 2,2'-Biphenyldiboronic Acid Pinacol Ester; 2,2'-Diboronic Acid Biphenyl Pinacol Ester; Biphenyl-2,2'-diylbis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane)
EINECS	Contact for details

Quality Control

Our 2,2'-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)biphenyl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for sensitive cross-coupling applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the product should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and when opening the container to prevent moisture absorption, which can compromise reactivity. Recommended storage temperature: 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.