Description

4-[[(2-Methylpropyl)Amino]Methyl]Phenylboronic Acid CAS NO 397843-60-6 is a specialized boronic acid derivative featuring an amino-methyl functional group, making it a valuable intermediate in modern synthetic chemistry. This compound is particularly significant for its role as a key building block in the synthesis of complex molecules via cross-coupling reactions. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its boronic acid functionality to create complex molecular architectures.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of organic electronic materials, sensors, and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Employed in the synthesis of activity-based probes and inhibitors that target specific enzymes or biological pathways.
• Catalyst Ligand Precursor: Acts as a starting material for synthesizing sophisticated ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific boronic acid derivatives.

Basic Information

Product Name	4-[[(2-Methylpropyl)Amino]Methyl]Phenylboronic Acid
CAS No.	397843-60-6
Molecular Formula	C11H18BNO2
Molecular Weight	207.08 g/mol
Synonyms	4-[(Isobutylamino)methyl]benzeneboronic acid; 4-(Isobutylaminomethyl)phenylboronic acid; p-[(Isobutylamino)methyl]phenylboronic acid; B-[4-[(2-Methylpropylamino)methyl]phenyl]boronic acid; 397843-60-6; 4-(Isobutylaminomethyl)benzeneboronic acid; 4-(Aminomethyl)-N-isobutylbenzeneboronic acid (related); Boronic acid, B-[4-[(2-methylpropylamino)methyl]phenyl]-
EINECS	Contact for details

Quality Control

Our 4-[[(2-Methylpropyl)Amino]Methyl]Phenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance for critical synthetic applications. Certificates of Analysis (COA) with full traceability are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.