Description

5-Methoxy-6-Nitropicolinaldehyde is a specialized aromatic aldehyde building block featuring both methoxy and nitro substituents on the pyridine ring. This compound is valued for its unique reactivity profile, where the aldehyde group serves as a versatile handle for condensation and cyclization reactions, while the nitro group can be further reduced or act as an electron-withdrawing substituent. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of complex heterocyclic compounds, including potential active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nitrogen-containing heterocycles for drug discovery programs.
• Agrochemical Synthesis: Used in the development of advanced crop protection agents and herbicides.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands in coordination chemistry.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for electronic or optical materials.
• Chemical Biology Probes: Useful for constructing molecular probes and tags due to its reactive aldehyde functionality.

Basic Information

Product Name	5-Methoxy-6-Nitropicolinaldehyde
CAS No.	397309-59-0
Molecular Formula	C8H8N2O4
Molecular Weight	196.16 g/mol
Synonyms	6-Nitro-5-methoxypicolinaldehyde; 5-Methoxy-6-nitro-2-pyridinecarboxaldehyde; 2-Pyridinecarboxaldehyde, 5-methoxy-6-nitro-; 5-Methoxy-6-nitropyridine-2-carbaldehyde
EINECS	Contact for details

Quality Control

Our 5-Methoxy-6-Nitropicolinaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after the original container has been opened.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.