Description

(3-Cyanomethylphenyl)Boronic Acid, Pinacol Ester is a high-purity, synthetically valuable boronic ester derivative, serving as a crucial building block in modern organic synthesis. Its primary value lies in enabling efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction, to construct complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries, where precise carbon-carbon bond formation is required.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides that require specific biphenyl or heterobiaryl structures.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Building block for organic electronic materials, including OLEDs and semiconductors, where conjugated systems are needed.
• Chemical Biology Probes: Utilized in the development of molecular probes and sensors due to its reactive boronate functionality.
• Custom Synthesis and Contract Manufacturing: A critical reagent for custom synthesis houses serving the life sciences and specialty chemicals markets.

Basic Information

Product Name	(3-Cyanomethylphenyl)Boronic Acid, Pinacol Ester
CAS No.	396131-82-1
Molecular Formula	C14H18BNO2
Molecular Weight	243.11 g/mol
Synonyms	(3-Cyanomethylphenyl)boronic acid pinacol ester; 3-(Cyanomethyl)benzeneboronic acid pinacol ester; (3-Cyanomethylphenyl)boronic acid neopentyl glycol ester (common alternative); Pinacol (3-Cyanomethylphenyl)boronate; B-[3-(Cyanomethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Cyanomethylphenylboronic Acid Pinacol Ester; (3-Cyanobenzyl)boronic acid pinacol ester (related name); CAS 396131-82-1
EINECS	Contact for details

Quality Control

Our (3-Cyanomethylphenyl)Boronic Acid, Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for sensitive coupling reactions. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of GMP environments for pharmaceutical intermediates and ISO standards for industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to prevent hydrolysis and maintain reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (NMR)	Conforms
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.