Description

4A(4H)-Naphthalenecarboxaldehyde, 1,5,8,8A-Tetrahydro-3,5-Dimethyl-1,4-Dioxo-, (4Ar,5R,8As)-Rel- (9Ci) is a specialized chiral naphthalene derivative that serves as a high-value synthetic intermediate. This compound is critical for research and development in advanced organic synthesis, particularly for constructing complex molecular architectures with defined stereochemistry. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs) and other high-performance materials.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, especially in therapeutic areas requiring complex, stereochemically defined molecules.
• Organic Synthesis Research: Used in academic and industrial R&D for methodological studies, including asymmetric synthesis, cycloaddition reactions, and the construction of polycyclic frameworks.
• Fine Chemical Production: Serves as a precursor for the manufacture of specialty chemicals, advanced materials, and ligands for catalysis.
• Agrochemical Development: Potential intermediate in the synthesis of new, more effective crop protection agents with specific biological activity.
• Material Science: Can be utilized in the development of organic electronic materials or novel polymers due to its naphthalene-based conjugated structure.

Basic Information

Item	Detail
Product Name	4A(4H)-Naphthalenecarboxaldehyde, 1,5,8,8A-Tetrahydro-3,5-Dimethyl-1,4-Dioxo-, (4Ar,5R,8As)-Rel- (9Ci)
CAS No.	395643-39-7
Molecular Formula	C13H16O3
Molecular Weight	220.26 g/mol
Synonyms	(4aR,5R,8aS)-rel-1,5,8,8a-Tetrahydro-3,5-dimethyl-1,4-dioxo-4a(4H)-naphthalenecarboxaldehyde; 4a(4H)-Naphthalenecarboxaldehyde, 1,5,8,8a-tetrahydro-3,5-dimethyl-1,4-dioxo-, (4aR,5R,8aS)-rel-; rel-(4aR,5R,8aS)-1,5,8,8a-Tetrahydro-3,5-dimethyl-1,4-dioxo-4a(4H)-naphthalenecarboxaldehyde
EINECS	Contact for details

Quality Control

Every batch of our 4A(4H)-Naphthalenecarboxaldehyde derivative is produced and tested under strict quality management systems to ensure high purity, consistent stereochemical integrity, and batch-to-batch reproducibility. Standard quality assurance includes comprehensive analysis via HPLC, GC, NMR, and chiral methods. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and specific impurity profiles to meet your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This compound is easily oxidized and light-sensitive; allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.