Description

4A(4H)-Naphthalenecarboxaldehyde, 1,5,8,8A-Tetrahydro-2,7-Dimethyl-1,4-Dioxo-, (4Ar,8As)-Rel- (9Ci) is a specialized chiral naphthalene derivative with a fused dioxo structure, serving as a high-value synthetic intermediate. Its precise stereochemistry and functional groups make it a critical building block for constructing complex molecular architectures in advanced research and development. This compound is essential for pharmaceutical chemists and material scientists working on novel active pharmaceutical ingredients (APIs), asymmetric catalysts, and functional organic materials.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel therapeutic agents and complex drug candidates.
• Asymmetric Catalysis: Used as a ligand or precursor for developing chiral catalysts in enantioselective synthesis.
• Organic Electronic Materials: Building block for research into n-type semiconductors, OLED materials, and other functional organic electronics due to its naphthalene core.
• Agrochemical Research: Intermediate in the development of new, targeted pesticides and herbicides with specific stereochemical requirements.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic synthesis, particularly in reactions involving aldehydes and diketones.
• Fine Chemical Synthesis: Used in the production of specialty dyes, pigments, and high-performance polymers requiring specific structural motifs.

Basic Information

Item	Detail
Product Name	4A(4H)-Naphthalenecarboxaldehyde, 1,5,8,8A-Tetrahydro-2,7-Dimethyl-1,4-Dioxo-, (4Ar,8As)-Rel- (9Ci)
CAS No.	395643-36-4
Molecular Formula	C₁₃H₁₄O₃
Molecular Weight	218.25 g/mol
Synonyms	rel-(4aR,8aS)-1,5,8,8a-Tetrahydro-2,7-dimethyl-1,4-dioxo-4a(4H)-naphthalenecarboxaldehyde; (4aR,8aS)-1,5,8,8a-Tetrahydro-2,7-dimethyl-1,4-dioxonaphthalene-4a(4H)-carbaldehyde; 4a(4H)-Naphthalenecarboxaldehyde, 1,5,8,8a-tetrahydro-2,7-dimethyl-1,4-dioxo-, (4aR,8aS)-rel-; 395643-36-4; Chiral naphthalene-dione aldehyde; Tetrahydrodimethyldioxonaphthalenecarboxaldehyde
EINECS	Contact for details

Quality Control

Every batch of 4A(4H)-Naphthalenecarboxaldehyde, 1,5,8,8A-Tetrahydro-2,7-Dimethyl-1,4-Dioxo-, (4Ar,8As)-Rel- (9Ci) is produced and controlled under a strict quality management system. Our products undergo rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity for demanding R&D and scale-up applications. Certificates of Analysis (COA) with full analytical data are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.