Description

Benzene, 1-Fluoro-4-(4-Pentynyl)- (9Ci) CAS NO 391678-43-6 is a specialized fluorinated aromatic compound featuring a terminal alkyne functional group. This unique bifunctional structure makes it a high-value building block in advanced organic synthesis, particularly for click chemistry and cross-coupling reactions. It is primarily utilized by pharmaceutical R&D and agrochemical laboratories for the development of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex drug candidates, especially in medicinal chemistry programs targeting new therapeutic entities.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its fluorine and alkyne groups for bioactivity.
• Material Science Research: Serves as a monomer or precursor in the development of advanced polymers and functional materials with specific electronic or surface properties.
• Click Chemistry Reagent: The terminal alkyne group enables efficient Huisgen cycloaddition (copper-catalyzed azide-alkyne cycloaddition) for bioconjugation and polymer functionalization.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for catalysis and molecular recognition applications.
• Fluorine Chemistry Studies: Acts as a model compound in research focused on the introduction and behavior of fluorine atoms in aromatic systems.

Basic Information

Product Name	Benzene, 1-Fluoro-4-(4-Pentynyl)- (9Ci)
CAS No.	391678-43-6
Molecular Formula	C11H11F
Molecular Weight	162.20 g/mol
Synonyms	1-Fluoro-4-(pent-4-yn-1-yl)benzene; 4-(4-Pentynyl)fluorobenzene; 4-Fluoro-1-(4-pentynyl)benzene; 1-(4-Pentynyl)-4-fluorobenzene; p-Fluorophenylpent-4-yne; (4-Fluorophenyl)pent-4-yne; 4-(4-Pentyn-1-yl)fluorobenzene
EINECS	Contact for details

Quality Control

Our high-purity Benzene, 1-Fluoro-4-(4-Pentynyl)- is manufactured under strict quality protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to confirm identity, purity, and the absence of critical impurities. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) due to its easily oxidized nature. Keep away from heat, sparks, and open flame. Due to high volatility, ensure containers are securely sealed when not in use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.