Description

5-Fluoro-6-Hydroxy-Naphthalene-1-Carboxylic Acid Methyl Ester is a high-purity fluorinated naphthalene derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both a fluorine substituent and a carboxylic acid methyl ester group, makes it an invaluable intermediate for creating complex molecules with tailored properties. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used to develop new herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Material Science: Building block for creating specialty polymers, liquid crystals, and organic electronic materials.
• Fluorescent Dye & Probe Synthesis: Serves as a core structure for developing advanced fluorescent markers and sensors used in bio-imaging and diagnostics.
• Academic & Contract Research: Essential reagent for methodological studies in organic chemistry and medicinal chemistry within university and CRO laboratories.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	5-Fluoro-6-Hydroxy-Naphthalene-1-Carboxylic Acid Methyl Ester
CAS No.	388622-47-7
Molecular Formula	C₁₃H₉FO₃
Molecular Weight	232.21 g/mol
Synonyms	Methyl 5-Fluoro-6-hydroxy-1-naphthoate; 1-Naphthalenecarboxylic acid, 5-fluoro-6-hydroxy-, methyl ester; 5-Fluoro-6-hydroxynaphthalene-1-carboxylic acid methyl ester; Methyl 5-fluoro-6-hydroxynaphthalene-1-carboxylate; 388622-47-7; 5-Fluoro-6-hydroxy-1-naphthoic acid methyl ester; 6-Hydroxy-5-fluoronaphthalene-1-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of 5-Fluoro-6-Hydroxy-Naphthalene-1-Carboxylic Acid Methyl Ester is manufactured under a strict quality management system. We employ advanced analytical techniques, including HPLC, GC-MS, and NMR, to ensure identity, purity, and consistency meet the exacting standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and reliability for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.