Description

2-(Methylsulfonyl)-1-[4-(Trifluoromethyl)Phenyl]Ethanone is a high-value, specialized organic intermediate featuring both a methylsulfonyl and a trifluoromethylphenyl group. This unique molecular structure makes it a critical building block for the synthesis of advanced pharmaceutical compounds and agrochemicals, where it imparts desirable metabolic stability and bioavailability. It is primarily sought after by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in kinase inhibitor and anti-inflammatory agent synthesis.
• Agrochemical Synthesis: Used as a precursor in the manufacture of advanced herbicides and fungicides, leveraging the trifluoromethyl group for enhanced efficacy.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced organic materials.
• Ligand and Catalyst Development: Employed in organic chemistry research for constructing complex molecular scaffolds and chiral ligands.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke production projects.

Basic Information

Product Name	2-(Methylsulfonyl)-1-[4-(Trifluoromethyl)Phenyl]Ethanone
CAS No.	386715-52-2
Molecular Formula	C10H9F3O3S
Molecular Weight	266.24 g/mol
Synonyms	1-[4-(Trifluoromethyl)phenyl]-2-(methylsulfonyl)ethanone; 2-Methylsulfonyl-1-[4-(trifluoromethyl)phenyl]ethanone; 4'-Trifluoromethyl 2-(methylsulfonyl)acetophenone; 2-(Methanesulfonyl)-1-[4-(trifluoromethyl)phenyl]ethan-1-one; α-(Methylsulfonyl)-4-(trifluoromethyl)acetophenone; NSC 405124; CAS 386715-52-2
EINECS	Contact for details

Quality Control

Every batch of 2-(Methylsulfonyl)-1-[4-(Trifluoromethyl)Phenyl]Ethanone is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for demanding R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.