Description

6-Bromo-2-(tert-Butyl)-5-Hydroxybenzofuran-3-Carboxylic Acid is a high-purity, synthetically valuable benzofuran derivative, serving as a critical advanced intermediate in modern organic synthesis. Its core value lies in its multifunctional chemical architecture, which provides a versatile scaffold for constructing complex molecules in pharmaceutical and agrochemical research. This compound is essential for R&D chemists and process development scientists working on novel active ingredients, particularly in the life sciences sector.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in therapeutic areas requiring complex heterocyclic cores.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its halogenated benzofuran structure.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialized polymers and organic electronic materials.
• Chemical Biology Probe Development: Utilized as a scaffold for creating molecular probes to study biological pathways and enzyme functions.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and discovery chemistry projects.

Basic Information

Product Name	6-Bromo-2-(tert-Butyl)-5-Hydroxybenzofuran-3-Carboxylic Acid
CAS No.	385390-94-3
Molecular Formula	C₁₃H₁₃BrO₄
Molecular Weight	313.15 g/mol
Synonyms	6-Bromo-2-tert-butyl-5-hydroxy-1-benzofuran-3-carboxylic acid; 2-(tert-Butyl)-6-bromo-5-hydroxybenzofuran-3-carboxylic acid; 5-Hydroxy-6-bromo-2-tert-butylbenzofuran-3-carboxylic acid; 385390-94-3; Benzofuran-3-carboxylic acid, 6-bromo-2-(1,1-dimethylethyl)-5-hydroxy-; 6-Bromo-5-hydroxy-2-tert-butylbenzofuran-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-(tert-Butyl)-5-Hydroxybenzofuran-3-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliance for advanced intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.