Description

1-(3-Fluoro-4-Pyrrolidin-1-Ylphenyl)Ethanone is a high-purity fluorinated aromatic ketone derivative featuring a pyrrolidine substituent. This compound serves as a critical advanced pharmaceutical intermediate (API intermediate) and a versatile building block in modern organic synthesis. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of potential drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active molecule libraries.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and insecticides with enhanced efficacy.
• Organic Synthesis: Serves as a versatile precursor for further functionalization via reactions at the ketone group or the aromatic ring, enabling the creation of complex molecular architectures.
• Material Science: Investigated as a monomer or additive in the synthesis of specialty polymers and advanced organic materials.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and activity-based protein profiling (ABPP) reagents.

Basic Information

Item	Details
Product Name	1-(3-Fluoro-4-Pyrrolidin-1-Ylphenyl)Ethanone
CAS No.	385380-85-8
Molecular Formula	C₁₂H₁₄FNO
Molecular Weight	207.25 g/mol
Synonyms	1-(3-Fluoro-4-(pyrrolidin-1-yl)phenyl)ethanone; 3'-Fluoro-4'-(pyrrolidin-1-yl)acetophenone; 1-[3-Fluoro-4-(1-pyrrolidinyl)phenyl]ethanone; 3-Fluoro-4-pyrrolidin-1-ylacetophenone; 385380-85-8; Ethanone, 1-[3-fluoro-4-(1-pyrrolidinyl)phenyl]-
EINECS	Contact for details

Quality Control

Our 1-(3-Fluoro-4-Pyrrolidin-1-Ylphenyl)Ethanone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles by HPLC/GC are provided with each shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.