Description

1,4-Thiazepine-3-Carboxylicacid,5-Amino-2,3,6,7-Tetrahydro-,Ethylester,(3S)-(9Ci) is a high-purity, stereochemically defined heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key chiral intermediate for the research and development of novel pharmaceutical agents, particularly those targeting the central nervous system and other therapeutic areas. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral scaffold in the synthesis of potential drug candidates, especially for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for hit-to-lead optimization.
• Process Chemistry Development: Employed in route scouting and scale-up studies for the production of active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Utilized as a building block to introduce the (3S) stereocenter into more complex molecules, leveraging its inherent chirality.
• Bioconjugation & Probe Development: The amino and ester functional groups allow for further derivatization to create chemical probes for biological studies.

Basic Information

Product Name	1,4-Thiazepine-3-Carboxylicacid,5-Amino-2,3,6,7-Tetrahydro-,Ethylester,(3S)-(9Ci)
CAS No.	384330-28-3
Molecular Formula	C8H14N2O2S
Molecular Weight	202.27 g/mol
Synonyms	(3S)-5-Amino-2,3,6,7-tetrahydro-1,4-thiazepine-3-carboxylic acid ethyl ester; Ethyl (3S)-5-amino-2,3,6,7-tetrahydro-1,4-thiazepine-3-carboxylate; 5-Amino-2,3,6,7-tetrahydro-1,4-thiazepine-3-carboxylic acid ethyl ester, (3S)-; (S)-Ethyl 5-amino-2,3,6,7-tetrahydro-1,4-thiazepine-3-carboxylate; 384330-28-3; 1,4-Thiazepine-3-carboxylic acid, 5-amino-2,3,6,7-tetrahydro-, ethyl ester, (3S)-; A chiral 1,4-thiazepine derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material that meets high-purity requirements for research and development use. Certificates of Analysis (COA) detailing identity, purity, and chiral purity are available upon request. Quality is assured through analytical techniques including HPLC, chiral HPLC, NMR, and mass spectrometry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.