Description

4-Bromo-1-Ethoxy-2-Nitrobenzene is a versatile halogenated nitroaromatic compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring bromine, ethoxy, and nitro substituents on a benzene ring, makes it a valuable precursor for constructing complex molecules. This intermediate is primarily sought after by research institutions and chemical manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in the development of heterocyclic compounds and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides due to its reactive halogen and nitro functional groups.
• Material Science Research: Employed as a monomer or precursor in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of complex azo dyes and other high-performance colorants.
• Cross-Coupling Reactions: Serves as a substrate in palladium-catalyzed reactions like Suzuki, Heck, and Buchwald-Hartwig aminations for carbon-carbon and carbon-heteroatom bond formation.
• Academic and R&D Laboratories: Utilized in methodological studies and as a standard reagent for exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	4-Bromo-1-Ethoxy-2-Nitrobenzene
CAS No.	383869-51-0
Molecular Formula	C8H8BrNO3
Molecular Weight	246.06 g/mol
Synonyms	1-Bromo-4-ethoxy-2-nitrobenzene; 4-Bromo-2-nitroanisole; 2-Nitro-4-bromoanisole; 4-Bromo-2-nitro-1-ethoxybenzene; 1-Ethoxy-4-bromo-2-nitrobenzene; 2-Nitro-4-bromo-1-ethoxybenzene; Benzene, 1-bromo-4-ethoxy-2-nitro-; p-Bromo-o-nitroanisole
EINECS	Contact for details

Quality Control

Our 4-Bromo-1-Ethoxy-2-Nitrobenzene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity determination, to meet the stringent requirements of our B2B clients in research and production. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.