Description

Difluoro-(4-Nitro-Phenoxy)-Acetic Acid Ethyl Ester is a specialized fluorinated organic ester building block of significant interest in advanced chemical synthesis. Its molecular structure, featuring both a nitroaromatic and a difluoroacetate moiety, makes it a valuable precursor for constructing complex molecules with tailored properties. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for use in medicinal chemistry and crop protection agent discovery.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for introducing fluorinated and nitro-substituted aromatic systems.
• Agrochemical Synthesis: Serves as a building block for creating advanced herbicides, fungicides, and insecticides where the difluoroacetate group can enhance biological activity and stability.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and organic electronic materials that require specific fluorinated aromatic components.
• Chemical Biology Probes: Utilized in the synthesis of fluorinated tags and probes for studying biological mechanisms and enzyme interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	Difluoro-(4-Nitro-Phenoxy)-Acetic Acid Ethyl Ester
CAS No.	383670-74-4
Molecular Formula	C10H9F2NO5
Molecular Weight	261.18 g/mol
Synonyms	Ethyl 2,2-difluoro-2-(4-nitrophenoxy)acetate; 2,2-Difluoro-2-(4-nitrophenoxy)acetic Acid Ethyl Ester; Ethyl [Difluoro(4-nitrophenoxy)acetate]; Acetic acid, 2,2-difluoro-2-(4-nitrophenoxy)-, ethyl ester; 4-Nitrophenyl 2,2-difluoro-2-ethoxy-2-oxoethyl ether
EINECS	Contact for details

Quality Control

Every batch of Difluoro-(4-Nitro-Phenoxy)-Acetic Acid Ethyl Ester is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements of research and process development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot and supplied with every order.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.