Description

1-(3-Iodophenyl)-1H-Pyrrole-2-Carboxaldehyde is a versatile and highly functionalized heterocyclic building block, serving as a critical intermediate in advanced organic synthesis. Its unique structure, featuring both an aldehyde and an iodophenyl group, makes it a valuable precursor for constructing complex molecules via cross-coupling and condensation reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its halogenated aromatic system for bioactivity.
• Material Science: Serves as a precursor for functional polymers, liquid crystals, and organic electronic materials due to its conjugated pyrrole-aldehyde system.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for Suzuki, Sonogashira, and other palladium-catalyzed coupling reactions to create biaryl structures.
• Ligand Synthesis: Used to prepare complex chelating ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology: Employed as a probe or linker in bioconjugation and the development of chemical tools for biological study.

Basic Information

Product Name	1-(3-Iodophenyl)-1H-Pyrrole-2-Carboxaldehyde
CAS No.	383136-22-9
Molecular Formula	C11H8INO
Molecular Weight	297.09 g/mol
Synonyms	1-(3-Iodophenyl)-1H-pyrrole-2-carboxaldehyde; 1H-Pyrrole-2-carboxaldehyde, 1-(3-iodophenyl)-; 3-(2-Formyl-1H-pyrrol-1-yl)iodobenzene; 1-(3-Iodophenyl)pyrrole-2-carbaldehyde; 1-(m-Iodophenyl)-1H-pyrrole-2-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 1-(3-Iodophenyl)-1H-Pyrrole-2-Carboxaldehyde is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.