Description

2-(4-(Ethylsulfonyl)Phenyl)Acetic Acid is a high-purity, functionalized phenylacetic acid derivative characterized by its ethylsulfonyl substituent, which imparts unique chemical reactivity and polarity. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis, enabling the development of novel active compounds. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating molecules with targeted biological or material properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of new drug candidates, particularly for anti-inflammatory and central nervous system (CNS) targeted therapies.
• Agrochemical Synthesis: Used as a precursor in the development of novel herbicides and fungicides, leveraging its sulfone moiety for bioactivity.
• Liquid Crystal & OLED Material Research: Acts as a building block for synthesizing advanced organic electronic materials due to its polar and planar structure.
• Organic Synthesis Reagent: Employed in coupling reactions (e.g., Suzuki, Heck) and as a precursor for other functionalized acetic acid derivatives in fine chemical production.
• Polymer Modification: Used to introduce sulfone groups into polymer chains to enhance thermal stability, solubility, or other material properties.

Basic Information

Product Name	2-(4-(Ethylsulfonyl)Phenyl)Acetic Acid
CAS No.	383135-47-5
Molecular Formula	C10H12O4S
Molecular Weight	228.26 g/mol
Synonyms	4-(Ethylsulfonyl)phenylacetic Acid; (4-Ethylsulfonylphenyl)acetic Acid; 2-[4-(Ethylsulfonyl)phenyl]acetic Acid; p-(Ethylsulfonyl)phenylacetic Acid; ESA; Ethylsulfonyl Phenyl Acetic Acid; Acetic acid, 2-[4-(ethylsulfonyl)phenyl]-; 383135-47-5
EINECS	Contact for details

Quality Control

Our production of 2-(4-(Ethylsulfonyl)Phenyl)Acetic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR to confirm identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support compliance with cGMP, ISO 9001, and REACH standards as required for global pharmaceutical and industrial supply chains.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed to minimize exposure to atmospheric moisture. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.