Description

4-[2-(Trifluoromethyl)Phenyl]-1,3-Thiazol-2-Amine is a specialized heterocyclic organic compound featuring a thiazole core substituted with a trifluoromethylphenyl group and an amine functionality. This molecular architecture makes it a valuable advanced pharmaceutical intermediate and a key building block in medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block for the research and development of new drug candidates, particularly in areas targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for the synthesis of specialized organic ligands, dyes, or functional polymers with unique electronic properties.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up manufacturing under cGMP conditions for clinical trial materials.

Basic Information

Product Name	4-[2-(Trifluoromethyl)Phenyl]-1,3-Thiazol-2-Amine
CAS No.	383129-63-3
Molecular Formula	C10H7F3N2S
Molecular Weight	244.24 g/mol
Synonyms	2-Amino-4-[2-(trifluoromethyl)phenyl]-1,3-thiazole; 4-(2-Trifluoromethylphenyl)-2-aminothiazole; 2-Amino-4-(α,α,α-trifluoro-o-tolyl)thiazole; 4-(2-(Trifluoromethyl)phenyl)thiazol-2-amine; 2-Thiazolamine, 4-[2-(trifluoromethyl)phenyl]-; AKOS BRN 0973; ZINC000257019789
EINECS	Contact for details

Quality Control

Our 4-[2-(Trifluoromethyl)Phenyl]-1,3-Thiazol-2-Amine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and MS analysis. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.