Description

2-(Diethylphosphonylmethyl)-5-Bromopyridine is a high-purity organophosphorus compound that serves as a critical building block in advanced chemical synthesis. Its unique molecular structure, featuring both a bromopyridine moiety and a diethylphosphonylmethyl group, makes it an exceptionally versatile intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting neurological disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of next-generation herbicides, insecticides, and fungicides, leveraging its phosphorus-containing structure.
• Ligand Synthesis: Serves as a starting material for creating sophisticated phosphine-based ligands used in catalysis and material science.
• Organic Electronics: Potential building block for novel organic semiconductors and light-emitting materials due to its conjugated pyridine system.
• Chemical Biology Probes: Employed in the design of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Cross-Coupling Reactions: The bromine atom makes it a suitable substrate for palladium-catalyzed cross-coupling reactions, such as Suzuki or Buchwald-Hartwig amination.

Basic Information

Product Name	2-(Diethylphosphonylmethyl)-5-Bromopyridine
CAS No.	380893-73-2
Molecular Formula	C10H15BrNO2P
Molecular Weight	292.11 g/mol
Synonyms	5-Bromo-2-[(diethoxyphosphinyl)methyl]pyridine; 5-Bromo-2-[(diethylphosphono)methyl]pyridine; Diethyl [(5-bromopyridin-2-yl)methyl]phosphonate; 2-[(Diethoxyphosphoryl)methyl]-5-bromopyridine; (5-Bromo-2-pyridylmethyl)phosphonic acid diethyl ester
EINECS	Contact for details

Quality Control

Our production of 2-(Diethylphosphonylmethyl)-5-Bromopyridine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.