Description

4-Chlorocarbonylphenylboronic Acid Propanediol Ester is a specialized organoboron compound that serves as a crucial protected boronic acid building block. This matters for synthetic chemists as it offers enhanced stability and solubility compared to its free boronic acid counterpart, facilitating handling and storage in demanding reaction environments. It is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for advanced organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions to construct complex biaryl structures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those containing biphenyl or substituted phenyl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
• Material Science Research: Employed in the creation of organic electronic materials, such as polymers and small molecules for OLEDs or OFETs, where precise molecular architecture is critical.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing sophisticated ligands used in transition metal catalysis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes, leveraging the reactivity of the masked boronic acid group.
• Custom Synthesis and Contract Manufacturing: A valuable reagent for fine chemical and custom synthesis houses serving the global life sciences market.

Basic Information

Product Name	4-Chlorocarbonylphenylboronic Acid Propanediol Ester
CAS No.	380499-68-3
Molecular Formula	C10H10BClO4
Molecular Weight	240.45 g/mol
Synonyms	4-(Chlorocarbonyl)phenylboronic acid 1,3-propanediol ester; 4-Carboxybenzene boronic acid propanediol ester chloride; (4-((1,3-Dioxolan-2-yl)phenyl)carbonyl chloride; Boronic acid, B-[4-(chlorocarbonyl)phenyl]-, 1,3-propanediol ester; 4-(1,3-Dioxolan-2-yl)benzoyl chloride (boronated); Protected 4-Carboxybenzene boronic acid; 4-Boronobenzoyl chloride propanediol cyclic ester
EINECS	Contact for details

Quality Control

Our 4-Chlorocarbonylphenylboronic Acid Propanediol Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.