Description

4-Methylbenzeneboronic Acid Neopentyl Ester is a specialized organoboron compound, specifically a sterically hindered arylboronic ester. This compound is valued for its enhanced stability and utility as a key synthetic intermediate in advanced organic transformations. It is primarily required by research and development chemists and process engineers in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A crucial reagent for forming carbon-carbon bonds between aryl groups, widely used in pharmaceutical and fine chemical synthesis.
• Pharmaceutical Intermediate: Serves as a building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: Employed in the preparation of novel ligands for transition metal catalysis.
• Functional Material Precursor: A key monomer or intermediate in the synthesis of organic electronic materials, such as OLEDs and semiconductors.
• Chemical Biology Probes: Utilized in the synthesis of bioconjugates and probes for studying biological processes.

Basic Information

Product Name	4-Methylbenzeneboronic Acid Neopentyl Ester
CAS No.	380481-66-3
Molecular Formula	C13H19BO2
Molecular Weight	218.10 g/mol
Synonyms	p-Tolylboronic Acid Neopentyl Ester; (4-Methylphenyl)boronic Acid Neopentyl Ester; Neopentyl 4-Methylbenzeneboronate; Neopentyl p-Tolylboronate; 4-Methylphenylboronic Acid Neopentyl Ester; Boronic acid, B-(4-methylphenyl)-, 2,2-dimethylpropyl ester; 380481-66-3; B-(4-Methylphenyl)-2,2-dimethylpropyl boronate
EINECS	Contact for details

Quality Control

Our 4-Methylbenzeneboronic Acid Neopentyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or when opening the container to prevent hydrolysis.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.