Description

3-Aminomethylphenylboronic Acid, Pinacol Ester, HCl is a protected boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in the dual functionality of the amine and the protected boronate group, enabling precise cross-coupling reactions and the construction of complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel biaryl compounds used in drug discovery and API development.
• Agrochemical Synthesis: Employed in the creation of advanced herbicides, fungicides, and insecticides that require specific boronic acid chemistry.
• Material Science: Used in the development of organic electronic materials, including OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the synthesis of activity-based probes and inhibitors.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing novel ligands and organocatalysts used in asymmetric synthesis.
• Academic & Contract Research: A valuable reagent for methodological research in organic synthesis and medicinal chemistry programs.

Basic Information

Product Name	3-Aminomethylphenylboronic Acid, Pinacol Ester, HCl
CAS No.	380430-65-9
Molecular Formula	C14H23BClNO2
Molecular Weight	283.60 g/mol
Synonyms	(3-(Aminomethyl)phenyl)boronic acid pinacol ester hydrochloride; 1-((3,4-Dihydro-2H-pyrrol-5-yl)methyl)-3-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid pinacol ester (related intermediate); 3-(Aminomethyl)benzeneboronic acid pinacol ester HCl; Benzeneboronic acid, 3-(aminomethyl)-, 1,1-dimethylethyl ester, hydrochloride; N-Boc-3-aminomethylphenylboronic acid pinacol ester (protected form); B-(3-(Aminomethyl)phenyl)-5,5-dimethyl-1,3,2-dioxaborinane hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Aminomethylphenylboronic Acid, Pinacol Ester, HCl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with full batch traceability are provided to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.