Description

(3-Benzyloxycarbonyl-5-Nitrophenyl)Boronic Acid is a specialized boronic acid derivative featuring both benzyloxycarbonyl and nitro functional groups on the aromatic ring. This compound is a critical synthetic intermediate in modern organic and medicinal chemistry, valued for its role in cross-coupling reactions and as a building block for complex molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new chemical entities, particularly for applications in drug discovery, materials science, and advanced organic synthesis.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a key boronic acid coupling partner for the synthesis of biaryl compounds, a common structural motif in pharmaceuticals and agrochemicals.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), especially for constructing complex molecular architectures.
• Protease Inhibitor Synthesis: Acts as a precursor in the synthesis of molecules designed to inhibit specific enzymes, such as proteases.
• Materials Science Research: Employed in the creation of novel organic electronic materials, ligands for catalysts, and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological processes and protein interactions.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and for scaling up target molecules.

Basic Information

Product Name	(3-Benzyloxycarbonyl-5-Nitrophenyl)Boronic Acid
CAS No.	380430-62-6
Molecular Formula	C14H12BNO6
Molecular Weight	301.06 g/mol
Synonyms	[3-[(Benzyloxy)carbonyl]-5-nitrophenyl]boronic acid; (3-Carbobenzyloxy-5-nitrophenyl)boronic acid; B-[3-[(Benzyloxy)carbonyl]-5-nitrophenyl]boronic acid; 3-(Benzyloxycarbonyl)-5-nitrobenzeneboronic acid; (Z)-5-Nitro-3-benzyloxycarbonylphenylboronic acid; Boronic acid, B-[3-[(phenylmethoxy)carbonyl]-5-nitrophenyl]-; 380430-62-6
EINECS	Contact for details

Quality Control

Our (3-Benzyloxycarbonyl-5-Nitrophenyl)Boronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity, identity, and impurity profiles. For specific project requirements, including custom purity grades or analytical method validation, please contact our technical support team.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.