Description

4-(Methylsulfonylamino)Phenylboronic Acid is a specialized organoboron compound featuring a phenylboronic acid core functionalized with a methylsulfonylamino group. This unique structure makes it a valuable building block in modern synthetic chemistry, particularly for Suzuki-Miyaura cross-coupling reactions. It is essential for researchers and manufacturers in the pharmaceutical and advanced materials sectors who require high-purity intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing biaryl structures.
• Suzuki-Miyaura Cross-Coupling: Serves as a critical boron reagent for forming carbon-carbon bonds between aromatic rings in drug discovery and development.
• Agrochemical Research: Used in creating novel compounds for crop protection and herbicide development.
• Material Science: Building block for organic electronic materials, such as polymers and small molecules for OLEDs or sensors.
• Chemical Biology: Utilized in the development of probes and inhibitors that interact with biological targets.
• Ligand Synthesis: Intermediate for creating sophisticated ligands used in catalysis.

Basic Information

Product Name	4-(Methylsulfonylamino)Phenylboronic Acid
CAS No.	380430-57-9
Molecular Formula	C7H10BNO4S
Molecular Weight	215.03 g/mol
Synonyms	4-(Methylsulfonylamino)benzeneboronic Acid; [4-(Methanesulfonylamino)phenyl]boronic Acid; N-(4-Boronophenyl)methanesulfonamide; 4-(Methanesulfonamido)phenylboronic Acid; B-[4-(Methylsulfonylamino)phenyl]boronic Acid; 4-(MSA)Phenylboronic Acid; 4-(Methylsulfonamido)benzeneboronic Acid
EINECS	Contact for details

Quality Control

Every batch of 4-(Methylsulfonylamino)Phenylboronic Acid is manufactured and tested under a strict quality management system. We provide comprehensive Certificates of Analysis (COA) that detail purity, identity, and impurity profiles, ensuring traceability and compliance with your research or production requirements. Our products are suitable for use under cGMP guidelines for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.