Description

3-Benzyloxycarbonylphenylboronic Acid is a high-purity boronic acid derivative featuring a benzyloxycarbonyl-protected aromatic ring, making it a versatile and valuable building block in advanced organic synthesis. Its primary value lies in its role as a key intermediate in cross-coupling reactions, enabling the precise construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly for developing active pharmaceutical ingredients (APIs) and functional organic materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A critical reagent for forming carbon-carbon bonds in the synthesis of biaryl compounds, a common scaffold in pharmaceuticals and organic electronics.
• Pharmaceutical Intermediate: Serves as a key building block in the research and production of novel drug candidates, especially in oncology and central nervous system (CNS) therapies.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs) for electronic and photonic applications.
• Chemical Biology & Proteomics: Acts as a handle for bioconjugation and the development of activity-based probes and inhibitors.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis services catering to R&D and pilot-scale production needs.

Basic Information

Product Name	3-Benzyloxycarbonylphenylboronic Acid
CAS No.	380430-52-4
Molecular Formula	C14H13BO4
Molecular Weight	256.06 g/mol
Synonyms	(3-((Benzyloxy)carbonyl)phenyl)boronic Acid; 3-Carboxybenzene boronic Acid Benzyl Ester; Benzyl 3-Boronobenzoate; 3-(Benzyloxycarbonyl)benzeneboronic Acid; B-[3-[(Benzyloxy)carbonyl]phenyl]boronic Acid; 3-Boronobenzoic Acid Benzyl Ester
EINECS	Contact for details

Quality Control

Our 3-Benzyloxycarbonylphenylboronic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We adhere to cGMP principles for pharmaceutical-grade intermediates, ensuring traceability and compliance with global regulatory expectations.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.