Description

4-Amino-5-Iodo-2-Methylbenzonitrile is a high-purity, halogenated aromatic nitrile building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in pharmaceutical research and agrochemical discovery. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of potential drug candidates, especially in kinase inhibitor and other targeted therapy research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, leveraging its halogen and nitrile functionalities.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and other advanced functional materials.
• Chemical Biology Probes: Useful for creating labeled compounds and molecular probes for biochemical and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for client-specific projects requiring this precise molecular scaffold.

Basic Information

Product Name	4-Amino-5-Iodo-2-Methylbenzonitrile
CAS No.	380241-62-3
Molecular Formula	C8H7IN2
Molecular Weight	258.06 g/mol
Synonyms	2-Methyl-4-amino-5-iodobenzonitrile; 5-Iodo-2-methyl-4-aminobenzonitrile; 4-Amino-5-iodo-2-methylbenzonitrile; Benzonitrile, 4-amino-5-iodo-2-methyl-; 2-Cyano-5-iodo-4-methylaniline; 4-Amino-5-iodo-o-tolunitrile
EINECS	Contact for details

Quality Control

Our 4-Amino-5-Iodo-2-Methylbenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.