Description

n-(4-Nitrobenzyl)-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline is a high-value, advanced pharmaceutical intermediate and building block in organic synthesis. This compound is critical for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily utilized in the pharmaceutical, agrochemical, and material science industries for applications requiring precise Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly for oncology and CNS-targeted therapies.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the formation of carbon-carbon bonds to create novel biaryl structures essential for modern medicinal chemistry.
• Agrochemical Research: Used in the development of new pesticides and herbicides with enhanced efficacy and selectivity.
• Material Science: Serves as a precursor for organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology Probes: Facilitates the creation of labeled compounds and probes for studying biological pathways and target engagement.
• Academic & R&D: A valuable reagent for synthetic organic chemistry research in university and industrial laboratories.

Basic Information

Item	Details
Product Name	n-(4-Nitrobenzyl)-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline
CAS No.	380152-00-1
Molecular Formula	C19H23BN2O4
Molecular Weight	354.21 g/mol
Synonyms	3-((4-Nitrobenzyl)amino)phenylboronic acid pinacol ester; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-(4-nitrobenzyl)aniline; N-(4-Nitrobenzyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenamine; Boronic acid, B-[3-[[(4-nitrophenyl)methyl]amino]phenyl]-, 1,1-dimethylethyl ester; 380152-00-1; 3-Amino-N-(4-nitrobenzyl)benzeneboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our n-(4-Nitrobenzyl)-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with stringent industry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.