Description

n-Benzyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline is a high-value, protected aniline boronic ester derivative, serving as a critical synthetic intermediate in modern organic chemistry. Its primary commercial value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone technology for constructing complex biaryl and heterobiaryl scaffolds. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity building blocks for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biphenyl or functionalized aniline motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
• Material Science: Serves as a monomer or precursor in the development of organic electronic materials, such as OLEDs, conductive polymers, and liquid crystals.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D labs exploring new catalytic cross-coupling methodologies and complex molecule synthesis.
• Ligand & Catalyst Preparation: Useful for constructing sophisticated nitrogen-containing ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and small-molecule libraries.

Basic Information

Product Name	n-Benzyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline
CAS No.	380151-99-5
Molecular Formula	C19H24BNO2
Molecular Weight	309.21 g/mol
Synonyms	3-(Benzylamino)phenylboronic acid pinacol ester; N-Benzyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenamine; [3-(Benzylamino)phenyl]boronic acid pinacol ester; 3-(N-Benzylamino)phenylboronic acid pinacol ester; Benzenamine, N-benzyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 380151-99-5; B-(3-(Benzylamino)phenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our n-Benzyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with relevant regulatory frameworks for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.