Description

3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-Benzaldehyde CAS NO 380151-86-0 is a high-purity, versatile boronic ester derivative featuring a reactive aldehyde functional group. This compound is a critical building block in modern synthetic organic chemistry, enabling efficient carbon-carbon bond formation through cross-coupling reactions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of complex molecules and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides requiring specific aromatic aldehyde-boronate functionalities.
• Material Science & OLED Development: Serves as a monomer or building block for creating organic light-emitting diodes (OLEDs), liquid crystals, and other functional organic electronic materials.
• Chemical Research & Development: Essential for academic and industrial R&D labs exploring new catalytic processes, ligand synthesis, and the construction of complex molecular architectures.
• Polymer Chemistry: Employed in the synthesis of specialty polymers and dendrimers where precise functional group placement is required.

Basic Information

Product Name	3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-Benzaldehyde
CAS No.	380151-86-0
Molecular Formula	C13H17BO3
Molecular Weight	232.09 g/mol
Synonyms	3-Formylphenylboronic acid pinacol ester; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde; 3-Aldehydephenylboronic acid pinacol ester; m-Formylphenylboronic acid pinacol ester; 3-(Pinacolatoboryl)benzaldehyde; Benzaldehyde, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 3-Carboxaldehydephenylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-Benzaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.