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2-Boronobenzaldehyde, Pinacol Ester CAS NO 380151-85-9
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CAS No.:380151-85-9
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-Boronobenzaldehyde, Pinacol Ester is a valuable organoboron building block, specifically a protected form of 2-formylphenylboronic acid. This compound matters for its enhanced stability and utility in cross-coupling reactions, particularly the Suzuki-Miyaura reaction, which is fundamental to modern pharmaceutical and agrochemical synthesis. It is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex biaryl and heterobiaryl structures.
Application
- Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling reactions.
- Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides by introducing the benzaldehyde moiety into complex molecules.
- Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and material science.
- Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where precise molecular architecture is critical.
- Chemical Biology Probes: Utilized to create tagged molecules for studying biological processes and protein interactions.
- Scale-up and Process Chemistry: Suitable for development from laboratory-scale research to pilot plant and commercial manufacturing processes.
Basic Information
| Product Name | 2-Boronobenzaldehyde, Pinacol Ester |
| CAS No. | 380151-85-9 |
| Molecular Formula | C₁₃H₁₇BO₃ |
| Molecular Weight | 232.08 g/mol |
| Synonyms | 2-Formylphenylboronic Acid Pinacol Ester; (2-Formylphenyl)boronic Acid Pinacol Ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde; 2-Aldehydephenylboronic Acid Pinacol Ester; 2-Boronobenzaldehyde Pinanediol Ester (common alternative); 2-Carboxybenzaldehyde Pinacol Boronate; PINACOL 2-FORMYLBENZENEBORONATE |
| EINECS | Contact for details |
Quality Control
Our 2-Boronobenzaldehyde, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request to support your quality assurance and regulatory documentation needs.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Assay (HPLC) | ≥97.0% |
| Purity (GC) | ≥98.0% |
| Water Content (KF) | ≤0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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