Description

3-Fluoro-n-[2-(Pyrrolidin-1-Ylcarbonyl)Phenyl]Benzamide is a sophisticated organic compound featuring a benzamide core linked to a fluorinated phenyl ring and a pyrrolidine carboxamide moiety. This molecular architecture makes it a valuable pharmacophore and chemical intermediate for advanced research and development. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of novel bioactive molecules, particularly in medicinal chemistry programs targeting enzyme inhibition and receptor modulation.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of potential new drug candidates, especially for central nervous system (CNS) and metabolic disorder targets.
• Medicinal Chemistry Research: Used as a core scaffold or derivatization point for structure-activity relationship (SAR) studies in drug discovery.
• Protease Inhibitor Development: The amide and pyrrolidine carbonyl groups suggest potential application in designing inhibitors for specific proteases or hydrolases.
• Chemical Biology Probes: Serves as a starting material for creating molecular probes to study biological pathways and protein function.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for producing complex, high-value specialty chemicals.
• Academic & Institutional Research: Used in university and research institute laboratories for exploratory synthetic chemistry and bioactivity screening projects.

Basic Information

Product Name	3-Fluoro-n-[2-(Pyrrolidin-1-Ylcarbonyl)Phenyl]Benzamide
CAS No.	378201-48-0
Molecular Formula	C18H17FN2O2
Molecular Weight	312.34 g/mol
Synonyms	3-Fluoro-N-[2-(1-pyrrolidinecarbonyl)phenyl]benzamide; 3-Fluoro-N-[2-(pyrrolidine-1-carbonyl)phenyl]benzamide; Benzamide, 3-fluoro-N-[2-(1-pyrrolidinylcarbonyl)phenyl]-; N-(2-(Pyrrolidine-1-carbonyl)phenyl)-3-fluorobenzamide; 378201-48-0; 3-Fluoro-N-(2-(pyrrolidine-1-carbonyl)phenyl)benzamide
EINECS	Contact for details

Quality Control

Our production of 3-Fluoro-n-[2-(Pyrrolidin-1-Ylcarbonyl)Phenyl]Benzamide adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are provided to ensure traceability and compliance with your research or manufacturing standards. We support cGMP principles for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.