Description

3-(2-Chloro-Phenyl)-Isoxazole-5-Carbaldehyde is a versatile and high-purity organic building block characterized by its reactive aldehyde group fused to an isoxazole ring. This compound matters as a critical intermediate for synthesizing complex molecules in pharmaceutical and agrochemical research, enabling the development of new active ingredients. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for constructing novel heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and anti-inflammatory agents.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging the biological activity of the isoxazole moiety.
• Material Science Precursor: Serves as a starting material for creating specialized ligands, catalysts, or functional polymers.
• Academic & Contract Research: Essential for methodological studies and library synthesis in university and CRO (Contract Research Organization) laboratories.
• Custom Synthesis: Employed in the production of tailored fine chemicals and advanced intermediates for specific client projects.

Basic Information

Product Name	3-(2-Chloro-Phenyl)-Isoxazole-5-Carbaldehyde
CAS No.	377051-52-0
Molecular Formula	C10H6ClNO2
Molecular Weight	207.61 g/mol
Synonyms	5-Formyl-3-(2-chlorophenyl)isoxazole; 3-(2-Chlorophenyl)-1,2-oxazole-5-carboxaldehyde; 3-(2-Chlorophenyl)isoxazole-5-carbaldehyde; 2-Chloro-3-isoaxazolecarboxaldehyde; (2-Chlorophenyl)-5-formylisoxazole; Isoxazole-5-carbaldehyde, 3-(2-chlorophenyl)-
EINECS	Contact for details

Quality Control

Our 3-(2-Chloro-Phenyl)-Isoxazole-5-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.